3-[2-[2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy]ethoxy]propanoic Acid
Mal-PEG2-acid
CAS: 1374666-32-6
Molecular Formula: C11H15NO6
3-[2-[2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy]ethoxy]propanoic Acid - Names and Identifiers
3-[2-[2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy]ethoxy]propanoic Acid - Physico-chemical Properties
| Molecular Formula | C11H15NO6 |
| Molar Mass | 257.24 |
| Density | 1.329±0.06 g/cm3(Predicted) |
| Boling Point | 455.7±35.0 °C(Predicted) |
| pKa | 4.27±0.10(Predicted) |
| Storage Condition | Room Temprature |
| Physical and Chemical Properties | Bioactive Mal-PEG2-acid is a non-cleavable ADC linker used to synthesize antibody-coupled drugs (ADC). Mal-PEG2-acid can be active with Tubulysin (HY-128914) and its cytotoxic derivatives. Mal-PEG2-acid can also be used as PROTAC linker for PROTAC synthesis. |
| In vitro study | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
3-[2-[2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy]ethoxy]propanoic Acid - Reference Information
| biological activity | Mal-PEG2-acid is a non-cleavable ADC linker used to synthesize antibody-coupled drugs (ADC). Mal-PEG2-acid can be active with Tubulysin (HY-128914) and its cytotoxic derivatives. Mal-PEG2-acid can also be used as PROTAC linker for PROTAC synthesis. |
| target | Non-cleavable PEGs |
| in vitro study | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
Last Update：2024-04-09 19:55:45
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View History
3-[2-[2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy]ethoxy]propanoic Acid
2-Amino-1-(3-Bromophenyl)Ethanone Hydrochloride(WX602205)
4-METHYLACETANILIDE
(E)-3-O-TOLYL-ACRYLOYL CHLORIDE
γ-Carboxyglutamic Acid γ,γ-Di-t-butyl Ester
硫酸阿巴卡韦杂质18
17-十八碳炔酸
Cyclopropanecarboxylic acid, 1-(4-nitrophenyl)-
1,5-二氨基-4,8-二羟基-9,10-蒽二酮
2-Amino-1-(3-Bromophenyl)Ethanone Hydrochloride(WX602205)
4-METHYLACETANILIDE
(E)-3-O-TOLYL-ACRYLOYL CHLORIDE
γ-Carboxyglutamic Acid γ,γ-Di-t-butyl Ester
硫酸阿巴卡韦杂质18
17-十八碳炔酸
Cyclopropanecarboxylic acid, 1-(4-nitrophenyl)-
1,5-二氨基-4,8-二羟基-9,10-蒽二酮